First 1000 Days of Life: Consequences of Antibiotics on Gut Microbiota

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Antibiotics and the gut microbiota

The effects of antibiotics on the indigenous microbes of the gut have been the subject of extensive study ever since the discovery of these drugs in the 1940s and their subsequent commercial production. Yet nearly all of this work has concerned the effects of individual antibiotics on individual, cultivated strains of bacteria in the laboratory, or on specific species of bacteria cultivated fro...

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Non-responsiveness or poor responsiveness to vaccines are challenging issues in vaccine development, and efforts have been made to find out the potential reasons for these conditions. Intestinal microbiome plays a key role in regulating and development of immune system and the composition and diversity of microbiota in different individuals on the one hand, and the imbalance of intestinal micro...

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From birth onwards, the human gut microbiota rapidly increases in diversity and reaches an adult-like stage at three years of age. After this age, the composition may fluctuate in response to external factors such as antibiotics. Previous studies have shown that resilience is not complete months after cessation of the antibiotic intake. However, little is known about the short-term effects of a...

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ژورنال

عنوان ژورنال: Frontiers in Microbiology

سال: 2021

ISSN: 1664-302X

DOI: 10.3389/fmicb.2021.681427